AmberLite 1600N

Summary

Product identification

AmberLite™XAD™1600N Polymeric Adsorbent is a macroporous, adsorbent resin supplied as white, insoluble beads in the fully hydrated form. It is designed for applications requiring the separation of similar species.

Typical Properties

Physical Properties

• Matrix: Macroporous, crosslinked DVB
• Type: Adsorbent
• Functional Group: None
• Physical Form: White, opaque, spherical beads
• Nitrogen BET Surface Area: ~800 m²/g
• Average Pore Diameter: ~150 Å
• Total Pore Volume: ~1.4 mL/mL

Chemical Properties

• Ionic Form as Shipped: Not applicable
• Total Exchange Capacity: Not applicable
• Water Retention Capacity: 66 – 73%

Particle Size

• Particle Diameter: 400 ± 50 µm
• Uniformity Coefficient: ≤ 1.25%
• Finer than 212 µm: ≤ 0.5%

Swelling (in solvent)

• Methanol: 15 – 20%
• 2-Propanol: 15 – 20%
• Acetone: 15 – 20%

Density

• Particle Density: 1.015 – 1.025 g/mL
• Shipping Weight: 660 g/L

Suggested Operating Conditions

• Maximum Operating Temperature: 150°C (302°F)
• pH Range (Stable): 1 – 14
• Bed Depth, min. (Chromatography): 1500 mm (4.9 ft)
• Flowrates:
  • Loading: 1 – 4 BV*/h (usually)
  • Elution/Desorption: 1 – 4 BV/h
  • Regeneration: 1 – 4 BV/h
  • Rinse: 1 – 8 BV/h

* 1 BV (Bed Volume) = 1 m³ solution per m³ resin or 7.5 gal per ft³ resin

Regenerants or Eluting Agents

• Water-miscible organic solvents (methanol, ethanol, isopropanol, acetone, etc.) for hydrophobic compounds
• Pure solvents for regenerating resin fouled by oils and antifoams
• Dilute bases (0.1 – 0.5% NaOH) for weakly acidic compounds
• Strong bases (2 – 4% NaOH) for regenerating resins fouled with proteins, peptides
• Dilute acids (0.1 – 0.5% HCl) for weakly basic compounds
• Dilute oxidizing agents (< 0.5%) such as peroxide to enhance the removal of protein fouling
• Buffer elution for pH-sensitive compounds
• Water when adsorption is from an ionic solution
• Hot nitrogen or steam for volatile materials

Hydraulic Characteristics

• Estimated bed expansion as a function of backwash flowrate and temperature is shown in Figure 4 (Temperature = 10 – 60°C).
• Estimated pressure drop as a function of service flowrate and water temperature is shown in Figure 5 (Temperature = 4.4 – 65.6°C). These expectations are valid at the start of the service run with clean feed.

Applications

• Recovery and purification of antibiotics, water-soluble steroids, amino acids, and proteins.
• Removal of non-polar compounds from polar solvents.

Pretreatment

AmberLite™XAD™1600N Polymeric Adsorbent is shipped water-wet with sodium chloride (NaCl) and sodium carbonate (Na₂CO₃) to inhibit bacterial growth. These salts must be washed from the adsorbent prior to use by washing with water at a linear flowrate of 5 – 10 m/h. A regeneration with the proposed regenerant is also recommended prior to the first service cycle. If the regenerant is an alcohol, it must be displaced with water prior to beginning the first loading cycle.

Product Stewardship

DuPont is committed to product stewardship, assessing safety, health, and environmental information and taking appropriate steps to protect employees, the public, and the environment.

Customer Notice: DuPont encourages customers to review manufacturing processes and applications of DuPont products to ensure they are not used in ways for which they are not intended or tested. Safety data sheets should be consulted prior to use.

WARNING: Oxidizing agents such as nitric acid can attack organic ion exchange resins, potentially leading to degradation or violent exothermic reactions. Consult knowledgeable sources before using strong oxidizing agents.

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Disclaimer: This extracted summary may not include all figures, footnotes, or revisions. Contractual data must match the OEM PDF revision used on the project.

Official datasheet (PDF)

Lenntech datasheet mirror