AmberChrom CG71M

Summary

Product identification

• Product Name: AmberChrom™ CG71M Chromatography Resin
• Product Type: Macroporous polymeric resin for adsorption and reversed-phase liquid chromatography.

Description

AmberChrom™ CG71M is a macroporous, rigid, insoluble, aliphatic (acrylic ester) polymer designed for large-scale purification of proteins, peptides, nucleic acids, antibiotics, and small molecular weight pharmaceutical ingredients. It is suitable for front-end capture, downstream purification, and desalting applications.

Key features include:

• Mechanically stable and chemically robust to standard reversed-phase solvents and cleaning agents.
• Highly hydrophilic.
• High surface area, unique pore size, and pore volume distribution, making it ideal for peptide separation.
• Narrow, controlled particle size distribution enabling high flow rates and high process throughput.
• High degree of chemical stability allowing operation across the entire pH range.
• Cleaned in place (CIP) with most organic solvents and dilute acids and bases.
• An alternative to RPC silica for high-resolution, low-pressure chromatography.

Applications

• Separation of small peptides
• Purification of aspartame

Typical Properties

Physical Properties

• Copolymer: Acrylic ester
• Matrix: Macroporous
• Type: Adsorbent
• Physical Form: Opaque, white, spherical beads
• Nitrogen BET Surface Area: 500 m²/g
• Average Pore Diameter: 250 Å

Chemical Properties

• Functional Group: None
• Shipping Solvent: 20% ethanol

Chemical Resistance

Insoluble in dilute solutions of acids or bases and common solvents: IPA, ACN, MeOH.

Particle Size

• Particle Diameter, mean: 75 µm
• Uniformity Coefficient: 1.7

Note: S-grade (35 µm) and C-grade (120 µm) are available as specialty products. The product can also be provided as a dry material upon request.

Stability (Swelling in solvent)

• Water: 0%
• Methanol: 2%
• Ethanol: 5%
• Isopropanol: 7%
• Acetonitrile: 7%
• Acetone: 6%
• Toluene: 4%
• Dry: -43%

Regulatory Status

DuPont can provide regulatory support for AmberChrom™ CG71M Chromatography Resin to end users under confidentiality, upon request.

Disclaimer

This extraction may miss figures, footnotes, or revisions. Contractual data must match the OEM PDF revision used on the project.

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WARNING: Oxidizing agents such as nitric acid attack organic ion exchange resins under certain conditions. This could lead to anything from slight resin degradation to a violent exothermic reaction (explosion). Before using strong oxidizing agents, consult sources knowledgeable in handling such materials.

Official datasheet (PDF)

Lenntech datasheet mirror