PPES

Summary

Product identification

PPES-Series High Purity Pharmaceutical Grade Polyethersulfone Filter Cartridges are designed for sterile filtration and clarification of pharmaceutical and biological solutions. They are integrity tested during manufacturing and supported by a validation guide for regulatory compliance.

Key characteristics:

• Low protein binding
• Broad chemical compatibility of polyethersulfone membrane
• Exceptional flow rate vs. pressure drop
• Fully validated as sterilizing grade filters in accordance with HIMA and ASTM F838-05 guidelines.
  • 0.2 micron series: Validated for 10⁷ Brevundimonas diminuta per cm² filter area.
  • 0.1 micron series: Validated for 10⁷ retention of Mycoplasma (Acholeplasma laidlawii) per cm² filter area.
• Designed to tolerate repeated hot water sanitization and in-situ steam sterilization cycles.
• Manufactured in a clean-room environment.

Typical Applications

• Vaccines
• Large Volume Parenteral (LVP’s)
• Water for Injection (WFI)
• Diagnostics
• Ophthalmics
• Cell and Tissue Culture Media
• Protein Solutions
• Serum and Blood Products

Construction Materials

• Membrane: Polyethersulfone
• Support Media: Polypropylene
• End Caps: Polypropylene
• Center Core: Polypropylene
• Outer Support Cage: Polypropylene
• O-Rings/Gaskets: Buna, EPDM, Silicone, Teflon® Encapsulated Viton®, Viton®, Teflon® Encapsulated Silicone
  • Note: O-ring adapters include integral reinforcement that will not deform with repeated steam sterilization or hot water sanitation cycles.

Operating limits

• Dimensions:
  • Length: 10 to 40 inches (25.4 to 101.6 cm) nominal
  • Outside Diameter: 2.78 inches (7.06 cm) nominal
• Change Out ΔP (recommended): 35 PSID
• Temperature (max): 176˚F (80˚C)
• Differential Pressure (max): 72 PSID (5.0 bar) at 68˚F (20˚C)

Sterilization

• Hot Water: 85°- 95°C, 30 min., max. ΔP 7 psi
• In-Line Steaming: 134°C, 30 min., max. ΔP 7 psi; 100 cycles

Compliance

• Toxicity: All polypropylene components meet the specifications for biological safety per USP Class VI – 121˚C for plastics.
• Food Safety: Materials of construction comply with FDA regulations for food and beverage contact use as detailed in 21CFR. Materials also deemed safe for use in contact with foodstuffs in accordance with EU Directives 2002/72/EC, 1935/2004, and/or 10/2011.

Ordering Information

The ordering code follows the format: PPES [Rating (µ)] [Length] [End Cap Style] [O-Rings/Gaskets]

• Rating (µ):
  • 0.1
  • 0.2
• Length:
  • 10” (25.4 cm)
  • 20” (50.8 cm)
  • 30” (76.2 cm)
  • 40” (101.6 cm)
• End Cap Style:
  • 2 = DOE Flat Gasket
  • 3 = 222 w/ Fin
  • 4 = 222 w/ Flat Cap
  • 6 = 226 w/ Flat Cap
  • 7 = 226 w/ Fin
  • 28 = 222 3-tabs w/ Fin
• O-Rings/Gaskets:
  • B = Buna-N
  • E = EPDM
  • S = Silicone
  • T = Teflon® Encapsulated Viton®
  • V = Viton®
  • Z = Teflon® Encapsulated Silicone

Flow Rate vs Pressure Drop

The document mentions "Flow Rate vs Pressure Drop" as a characteristic of the PPES-Series Pharmaceutical Grade Polyethersulfone filters, but specific data or curves are not provided in this extract. See the official PDF for exact tabulated values.

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Disclaimer: This summary is based on extracted text and may not include all figures, footnotes, or the latest revisions. Contractual data must match the OEM PDF revision used on the project.

Official datasheet (PDF)

Lenntech datasheet mirror