PPTFE

Summary

Product Identification

PPTFE-Series High Purity Pharmaceutical Grade PTFE Filter Cartridges are designed with an expanded polytetrafluoroethylene (PTFE) membrane for optimized filtration performance in sterile air/gas filtration and venting applications. The single-layer PTFE membrane offers over twice the hydrophobicity of polypropylene or PVDF, helping to prevent water intrusion and microbial growth. Each PPTFE cartridge is integrity tested during manufacturing and is supported by a validation guide for regulatory compliance. PPTFE elements are fully validated as sterilizing grade filters in liquids (HIMA and ASTM F838-05 guidelines) and in gases (full retention of the MS2 phage in an aerosol challenge). Products are manufactured in a clean-room environment.

Typical Applications:

• Sterile gas filtration of fermentor inlets
• Off-gassing downstream of fermentors and bioreactors
• Autoclave vent filters
• WFI tank vents
• Sterile air supply for service gases (e.g., filling lines in blow-fill-seal systems)

Operating Limits

• Change Out ΔP (recommended): 35 PSID
• Temperature (max): 248˚F (120˚C)
• Differential Pressure (max): 72 PSID (5.0 bar) at 68˚F (20˚C)

Mechanical / Hydraulic

Construction Materials:

• Membrane: PTFE
• Prefiltration Media: Polypropylene
• Support Layers: Polypropylene
• Cage/Core/Adapters: Polypropylene
• Seals: Buna, EPDM, Silicone, Viton®, Teflon® Encapsulated Silicone
  • Note: O-ring adapters include integral reinforcement that will not deform with repeated steam sterilization or hot water sanitation cycles.

Dimensions:

• Length: 5 to 40 inches (12.7 to 101.6 cm) nominal
• Outside Diameter: 2.78 inches (7.06 cm) nominal

Sanitization/Sterilization:

• Steam Sterilization: 134°C, 30 min., max. 7 PSID, 150 cycles
• Hot Water: 85°- 95°C, 30 min., max. 7 PSID

Flow Rate vs Pressure Drop: A chart showing Flow Rate vs Pressure Drop for PPTFE-Series Pharmaceutical Grade PTFE is available in the official PDF.

Compliance and Certifications

Toxicity: All polypropylene components meet the specifications for biological safety per USP Class VI – 121˚C for plastics.

Food Safety Compliance: Materials of construction comply with FDA regulations for food and beverage contact use as detailed in the US Code of Federal Regulations, 21CFR. Materials used to produce filter media and hardware are deemed safe for use in contact with foodstuffs in accordance with EU Directives 2002/72/EC, 1935/2004, and/or 10/2011.

Ordering Information

The ordering code follows the format: PPTFE [Rating (µ)] [Length] [End Cap Style] [O-Rings/Gaskets]

Available Options:

• Rating (µ): 0.2
• Length:
  • 5” (12.7 cm)
  • 10” (25.4 cm)
  • 20” (50.8 cm)
  • 30” (76.2 cm)
  • 40” (101.6 cm)
• End Cap Style:
  • 2 = DOE Flat Gasket
  • 3 = 222 w/ Fin
  • 4 = 222 w/ Flat Cap
  • 6 = 226 w/ Flat Cap
  • 7 = 226 w/ Fin
  • 28 = 222 3-tabs w/ Fin
• O-Rings/Gaskets:
  • B = Buna
  • E = EPDM
  • S = Silicone
  • T = Teflon® Encapsulated Viton®
  • V = Viton®
  • Z = Teflon® Encapsulated Silicone

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Disclaimer: extraction may miss figures, footnotes, or revisions; contractual data must match the OEM PDF revision used on the project.

Official datasheet (PDF)

Lenntech datasheet mirror