Datasheet summary
Membralox ceramique elements
Engineering summary from PDF text extraction for Membralox ceramique elements. Verify every value with the OEM datasheet.
Summary
Product Identification
Pall's Membralox® ceramic membrane elements are designed for biopharmaceutical applications involving extreme processes such as high solids bulk processes, high temperatures or pressures, or aggressive solvents, requiring significant long-term durability.
Available ratings range from very low molecular weight ultrafiltration for duties like unwanted protein removal from antibiotic solutions, through to open microfiltration membranes (up to 5 µm) for processing difficult materials like microspheres or clarifying solvent-based plant extracts in transgenic processes. The elements feature an asymmetric membrane structure and compact multi-channel geometry optimized for bulk processing.
Membralox membrane elements are available in 3 different channel diameters for solids loading optimization. Some configurations offer unique longitudinal permeability gradients to control permeate rate along the module length. Sizes range from small laboratory devices to individual modules with over 20 square meters surface area.
Materials of Construction
Membralox ceramic membranes consist of a highly controlled surface membrane layer formed on the inner (feed-side) surface of a more open support layer.
- Membrane Materials: Ultrapure, α alumina, zirconia, and titania. All are FDA-listed for pharmaceutical processes.
- Membralox SD Sanitary Modules: Wetted materials: 316L SS, ceramic, EPDM or FPM.
- Membralox HCB Industrial Modules: Wetted materials: 316L SS, ceramic, PTFE.
- Membralox T1-70 Modules: Housing material: 316L SS.
Operating Limits
Aqueous Liquids
- Temperature: 95 °C (203 °F)
- Pressure: 8 – 10 barg (depending on module selected)
- Differential Back Pressure: 8 bard
- pH Compatibility: 0 – 14
Specifications
Membrane Element Configurations
These elements are made of Ultrapure alumina (>99.7%).
| Element Type | Channel Diameter | Number of Channels | Filtration Surface Area | Length |
|---|---|---|---|---|
| P37 – 30 | 3 mm | 37 | 0.35 m² (3.77 ft²) | 1020 mm |
| P19 – 40 | 4 mm | 19 | 0.24 m² (2.58 ft²) | 1020 mm |
| P19 – 60 | 6 mm | 19 | 0.36 m² (3.88 ft²) | 1020 mm |
Membrane Pore Sizes
- Microfiltration:
- 5.0 µm (α alumina)
- 2.0 µm (α alumina)
- 1.4* µm (α alumina)
- 0.8* µm (α alumina)
- 0.5* µm (α alumina)
- 0.2* µm (α alumina)
- 0.1* µm (α alumina)
- Ultrafiltration:
- 100 nm (zirconia)
- 50 nm (zirconia)
- 20 nm (zirconia)
- 5000 Da MWCO (titania)
- 1000 Da MWCO (titania)
*Available in Membralox GP membrane version.
Membralox SD Sanitary Modules
- Element Type P19 – 60
- Number of Membranes: 1 – 3 – 12 – 22
- Filtration Surface Area: up to 7.9 m² (85 ft²)
- Permeate Connections: Sanitary clamps/3A gaskets
- Element Type P19 – 40/P37 – 30
- Number of Membranes: 1 – 3 – 7 – 19 – 37
- Filtration Surface Area: up to 13.0 m² (140 ft²)
- Permeate Connections: Sanitary clamps/3A gaskets
Membralox HCB Industrial Modules
| Part Number | Element Type | Number of Membranes | Filtration Surface Area | Retentate Connections | Permeate Connections |
|---|---|---|---|---|---|
| 36P2 | P19-60 | 36 | 13.0 m² | Bolt flanges with O-rings | Bolt flanges with flat gaskets |
| 60P1 | P19-40/P37-30 | 60 | 14.4/21.0 m² | Bolt flanges with O-rings | Bolt flanges with flat gaskets |
Membralox T1-70 Modules
These modules are suitable for use with Pall laboratory and pilot-scale test systems.
- Channel Diameter: 7 mm
- Length: 250 mm
- Filtration Surface Area: 0.005 m² (0.054 ft²)
- Housing Material: 316L SS
- Permeate Hold-up Volume: 7 mL
Features and Benefits
- Reliability
- Ease of use
- High flux
- Proven long operational life
- Wide chemical and pH (0 – 14) compatibility
- Excellent thermal stability
- Sanitizable and sterilizable
- Element burst pressure > 50 bar
- Ability to withstand high frequency backpulsing cycles
- Components are FDA-listed in 21 CFR Part 11
- 100% bubble point integrity-tested
- Near zero non-specific adsorption of biological materials (ceramic membranes)
- High membrane packing density up to 240 m²/m³ (2583 ft²/ft³) (HCB modules)
- Reduced permeate hold-up volume (HCB and T1-70 modules)
- High-performance sealing assembly with gasket leak detection (SD modules)
- Modules and membrane components fully traceable
Application
- Biopharmaceutical Applications
- Clarification of bulk fermentation broths
- Protein removal from antibiotics
- Processing of alginates and other excipients
- Clarification of solvent extracts
- Pyrogen and bacteria removal in high purity systems
Disclaimer: This summary is based on extracted text and may not include all figures, footnotes, or the latest revisions. Contractual data must match the OEM PDF revision used on the project.
Official datasheet (PDF)
Curated from selected public technical reference material for discovery and preliminary comparison. This summary is not a substitute for a current certified manufacturer datasheet. Verify revisions and design limits before use.