Spirapro HFK 4333-K131-VSV Pharmaceutical

Summary

Product identification

SPIRAPRO™ HFK™ PHARMACEUTICAL GRADE UF ELEMENTS are ultrafiltration 4-inch and 8-inch spiral element series.

• Membrane Chemistry: Proprietary semi-permeable polyethersulfone (PES)
• Membrane Type:
  • HFK™-131 with observed separation range of 10,000 Daltons
  • HFK™-328 with observed separation range of 5,000 Daltons
• Construction: Sanitary spiral wound element with net outer wrap
• Feed Spacer: V (46 mil)
• Permeate Tube: Stainless steel
• Applications: Enzyme purification, protein concentration, and protein fractionation
• Regulatory Status: Conform to FDA food-contact regulations (CFR Title 21)
• Options:
  • Outer wrap: Controlled (VSV) or trimmable (VST)
  • Diameter: 4.3” or 8.3”
• Active Membrane Area:
  • SPIRAPRO,4333-K131-VSV: 75 ft² (7.0 m²)
  • SPIRAPRO,8333-K131-VST: 278 ft² (25.8 m²)
  • SPIRAPRO,8333-K328-VST: 286 ft² (26.6 m²)
• Pure Water Flux: 1.0-2.2 gfd/psi (24-53 l/m²/h/bar) at 77°F (25°C)

Operating limits

• Typical Operating Pressure: 30 - 120 psi (2.1 - 8.3 bar)
• Maximum Operating Pressure: 140 psi (9.7 bar)
• Operating Temperature Range: 41 - 131°F (5 - 55°C)
• Cleaning Temperature Range: 105 - 122°F (40 - 50°C)
• Allowable pH - Continuous Operation: 2.0 - 10.0
• Allowable pH - Clean-In-Place (CIP): 1.8 - 11.0

Feed water

• Turbidity: Maximum 1 NTU
• SDI: Maximum 5.0 (15-minute test)

Mechanical / hydraulic

• Design Pressure Drop Per Element: 15-20 psi (1.0-1.4 bar)
• Design Pressure Drop Per Vessel (3 in series): 45-60 psi (3.1-4.1 bar)
• Design Pressure Drop Per Vessel (4 in series): 60-68 psi (4.1-4.7 bar)
• Nominal Dimensions (reference only):
  • 4333 models:
    • A: 37.0 inches (940 mm)
    • B: 4.3 inches (109 mm)
    • C: 0.811 inches (20.6 mm)
    • D: 33.0 inches (838 mm)
  • 8333 models:
    • A: 36.7 inches (933 mm)
    • B: 8.3 inches (211 mm)
    • C: 1.632 inches (41.5 mm)
    • D: 33.0 inches (838 mm)

Special Conditions / Warnings

• Permeate Pressure: Should not exceed baseline (concentrate) pressure at any time. Reverse pressure will damage the membrane.
• Chlorine Exposure:
  • Recommended exposure time: 30 minutes per day.
  • Residual chlorine concentration during CIP: 150 ppm @ pH 10.5 or higher.
  • Maximum chlorine concentration: 200 ppm.
  • Chlorine should only be added to the cleaning solution after pH has been adjusted to 10.5 or higher.
  • Iron or other catalyzing metals in the presence of free chlorine or hydrogen peroxide will accelerate membrane degradation.
• Cationic Polymers and Surfactants: Exposure may irreversibly foul HFK membranes and is not recommended. It will void the warranty.
• Lubricants: For element installation, use only water or glycerin to lubricate seals. Petroleum or vegetable-based oils or solvents may damage the element and will void the warranty.

Disclaimer: This summary is based on extracted text and may not include all figures, footnotes, or the latest revisions. Contractual data must match the OEM PDF revision used on the project.

Official datasheet (PDF)

PDF datasheet